The Biostatistics and Data Management Core leads the Center efforts on design and analysis of all experiments conducted in all Projects. Core staff conduct statistical analyses using modern, state-of-the-art statistical models and methods. The Biostatistics & Data Management Core develops a HIPAA-compliant database for data from all Project I & III, and is responsible for transmitting CDE data to the NINDS Data Management Resource. The Biostatistics & Data Management Core collaborates with the Neuroimaging Resource Core on multimodal analyses of imaging datasets. It is also instrumental in training students and fellows to develop skills and expertise in analysis of imaging datasets, database management, and trial activities.